What to expect

What to expect with Minivelle®

There are both benefits and risks associated with Minivelle

What to Expect

Minivelle (estradiol transdermal system) is the world's smallest estrogen therapy (ET) patch to reduce moderate to severe hot flashes and night sweats due to menopause and to help prevent postmenopausal osteoporosis. Minivelle, like all estrogen therapies, has side effects and risks.

Risks of ET

Below is the most important information you should know about Minivelle.

  • Using estrogen-alone may increase your chance of getting cancer of the uterus (womb). Report any unusual vaginal bleeding right away while you are using Minivelle as vaginal bleeding after menopause may be a warning sign of cancer of the uterus. Your healthcare provider should check any unusual vaginal bleeding to find out the cause.

  • Do not use estrogen-alone or estrogen with progestins to prevent heart disease, heart attacks, strokes, or dementia (decline in brain function).

  • Using estrogen-alone may increase your chances of getting strokes or blood clots, while using estrogens with progestins may increase your chances of getting heart attacks, strokes, breast cancer, or blood clots.

  • Using estrogen-alone or estrogen with progestins may increase your chance of getting dementia, based on a study of women 65 years of age or older.

Doctors are likely to start you on the lowest effective dose of estrogen. You and your doctor should talk regularly (for example, every 3 to 6 months) about the dose you are using and whether you still need treatment with Minivelle.

If you use Minivelle only to prevent osteoporosis from menopause, talk with your healthcare provider about whether a different treatment or medicine without estrogens might be better for you.

Common side effects

The most common side effects that may occur with Minivelle are headache, breast tenderness, back and limb pain, common cold, upset stomach, nausea, inflammation of the sinuses and irregular vaginal bleeding or spotting.

Start the conversation

Is estrogen therapy right for me?

Complete and print this guide to start the conversation with your doctor.

Menopause Symptom Checklist

While menopause has many symptoms, the most common are hot flashes and night sweats. Some hot flashes and night sweats are easily tolerated, some annoying or embarrassing, while others can be very uncomfortable. Use this checklist to record your observations and let your doctor know what symptoms you may be experiencing.

Please note: this checklist is not a substitute for professional medical advice. Only a doctor or other qualified healthcare provider can diagnose hot flashes due to menopause.

Chart your symptoms below:

  1. How often do you experience hot flashes (a sudden wave of heat)?

    • Many times a day

    • Many times per week

    • A few times per month

    • Never

  2. How much of an impact do hot flashes have on your daily life?

    • They are very bothersome

    • They bother me a little

    • They don't bother me at all

  3. How often do you experience night sweats (hot flashes with excessive sweating that occur at night)?

    • Every night

    • Many nights per week

    • A few nights per month

    • Never

  4. How much of an impact do your night sweats have?

    • They bother me a lot

    • They sometimes bother me

    • They hardly ever bother me

  5. How long have you been experiencing hot flashes and/or night sweats?

    • 5-10 years

    • 2-4 years

    • 12-24 months

    • Less than 12 months

  6. How are you treating your menopausal symptoms?

    • Have made lifestyle changes, but haven’t sought out treatment

    • Currently take estrogen therapy

    • Currently take over-the-counter medicines or dietary supplements

  7. What are you doing to reduce your risk of postmenopausal osteoporosis (thin weak bones)?

    • I am taking steps to prevent osteoporosis

    • I would like help preventing osteoporosis

    • I am not worried about osteoporosis

Questions for Your Doctor

Select the questions that are most important to you, then add your own to help in your discussion.

  • Menopause symptoms

    • What are the most common symptoms of menopause?

    • How long will the symptoms last?

    • Would a hysterectomy cause me to go into menopause?

  • Treatment options

    • Which type of treatment do you recommend for me?

    • Is estrogen therapy right for me?

    • Why should I consider an estrogen therapy patch?

  • About Minivelle® (estradiol transdermal system)

    • Is Minivelle an option for me?

    • How may Minivelle help with my symptoms?

    • What should I know about risks and side effects associated with Minivelle?

    • If I’m looking for a plant-based or bioidentical ET, could Minivelle be right for me?

  • Switching to Minivelle®

    • If I’m currently on Vivelle-Dot® for moderate to severe hot flashes and night sweats and would like to use Minivelle, am I a candidate to switch?

  • Additional questions

The information provided here is general in nature and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. You are strongly encouraged to seek the advice of your doctor or other qualified healthcare provider with any questions regarding a medical condition.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about MINIVELLE® (an estrogen hormone)?

  • Using estrogen-alone may increase your chance of getting cancer of the uterus (womb). Report any unusual vaginal bleeding right away while you are using MINIVELLE® as vaginal bleeding after menopause may be a warning sign of cancer of the uterus. Your healthcare provider should check any unusual vaginal bleeding to find out the cause.

  • Do not use estrogen-alone or estrogen with progestins to prevent heart disease, heart attacks, strokes, or dementia (decline in brain function).

  • Using estrogen-alone may increase your chances of getting strokes or blood clots, while using estrogens with progestins may increase your chances of getting heart attacks, strokes, breast cancer, or blood clots.

  • Using estrogen-alone or estrogen with progestins may increase your chance of getting dementia, based on a study of women 65 years of age or older.

  • You and your healthcare provider should talk regularly about whether you still need treatment with MINIVELLE®.

MINIVELLE® should not be used if you have unusual vaginal bleeding, currently have or have had certain cancers, had a stroke or heart attack, currently have or have had blood clots, currently have or have had liver problems, have been diagnosed with a bleeding disorder, are allergic to MINIVELLE® or any of its ingredients, or think you may be pregnant.

Before you take MINIVELLE, tell your healthcare provider if you have unusual vaginal bleeding, have any other medical conditions, are going to have surgery or will be on bed rest, are breast feeding, and about all of the medicines you take.

The most common side effects that may occur with MINIVELLE are headache, breast tenderness, back and limb pain, common cold, upset stomach, nausea, inflammation of the sinuses and irregular vaginal bleeding or spotting.

MINIVELLE should be used at the lowest effective dose and for the shortest duration consistent with your treatment goals and risks.

These are not all the possible side effects of MINIVELLE. Please read the Patient Information section within the full Prescribing Information before taking MINIVELLE. For more information ask your healthcare provider or pharmacist for advice about side effects.

INDICATION

MINIVELLE® (estradiol transdermal system) is a prescription medicine patch that contains estradiol (an estrogen hormone). MINIVELLE® is used to reduce moderate to severe hot flashes due to menopause and to help prevent postmenopausal osteoporosis (thin weak bones). The 0.025 mg/day dose is only approved for the prevention of postmenopausal osteoporosis.

If you use MINIVELLE® only to prevent osteoporosis from menopause, talk with your healthcare provider about whether a different treatment or medicine without estrogens might be better for you.

Click here for the full Prescribing Information, including Boxed WARNING.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088.


IMPORTANT SAFETY INFORMATION

What is the most important information I should know about MINIVELLE® (an estrogen hormone)?

  • Using estrogen-alone may increase your chance of getting cancer of the uterus (womb). Report any unusual vaginal bleeding right away while you are using MINIVELLE as vaginal bleeding after menopause may be a warning sign of cancer of the uterus. Your healthcare provider should check any unusual vaginal bleeding to find out the cause.

  • Do not use estrogen-alone or estrogen with progestins to prevent heart disease, heart attacks, strokes, or dementia (decline in brain function).

  • Using estrogen-alone may increase your chances of getting strokes or blood clots, while using estrogens with progestins may increase your chances of getting heart attacks, strokes, breast cancer, or blood clots.

  • Using estrogen-alone or estrogen with progestins may increase your chance of getting dementia, based on a study of women 65 years of age or older.

  • You and your healthcare provider should talk regularly about whether you still need treatment with MINIVELLE.

MINIVELLE should not be used if you have unusual vaginal bleeding, currently have or have had certain cancers, had a stroke or heart attack, currently have or have had blood clots, currently have or have had liver problems, have been diagnosed with a bleeding disorder, are allergic to MINIVELLE or any of its ingredients, or think you may be pregnant.

Before you take MINIVELLE, tell your healthcare provider if you have unusual vaginal bleeding, have any other medical conditions, are going to have surgery or will be on bed rest, are breast feeding, and about all of the medicines you take.

The most common side effects that may occur with MINIVELLE are headache, breast tenderness, back and limb pain, common cold, upset stomach, nausea, inflammation of the sinuses and irregular vaginal bleeding or spotting.

MINIVELLE should be used at the lowest effective dose and for the shortest duration consistent with your treatment goals and risks.

These are not all the possible side effects of MINIVELLE. Please read the Patient Information section within the full Prescribing Information before taking MINIVELLE. For more information ask your healthcare provider or pharmacist for advice about side effects.

INDICATION

MINIVELLE® (estradiol transdermal system) is a prescription medicine patch that contains estradiol (an estrogen hormone). MINIVELLE is used to reduce moderate to severe hot flashes due to menopause and to help prevent postmenopausal osteoporosis (thin weak bones). The 0.025 mg/day dose is only approved for the prevention of postmenopausal osteoporosis.

If you use MINIVELLE only to prevent osteoporosis from menopause, talk with your healthcare provider about whether a different treatment or medicine without estrogens might be better for you.

Click here for the full Prescribing Information, including Boxed WARNING.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088.


DOT Matrix™ is a trademark of Noven Pharmaceuticals, Inc.

MINIVELLE® and the Minivelle Logo are trademarks of Noven Therapeutics, LLC.

Vivelle-Dot® is a registered trademark of Novartis AG.

For information, call 1-800-455-8070.

©2017-2018 Noven Therapeutics, LLC. All rights reserved. For U.S. Audience Only. MINI-3530-16 10/18

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about MINIVELLE® (an estrogen hormone)?

  • Using estrogen-alone may increase your chance of getting cancer of the uterus (womb). Report any unusual vaginal bleeding right away while you are using MINIVELLE as vaginal bleeding after menopause may be a warning sign of cancer of the uterus. Your healthcare provider should check any unusual vaginal bleeding to find out the cause.

  • Do not use estrogen-alone or estrogen with progestins to prevent heart disease, heart attacks, strokes, or dementia (decline in brain function).

  • Using estrogen-alone may increase your chances of getting strokes or blood clots, while using estrogens with progestins may increase your chances of getting heart attacks, strokes, breast cancer, or blood clots.

  • Using estrogen-alone or estrogen with progestins may increase your chance of getting dementia, based on a study of women 65 years of age or older.

  • You and your healthcare provider should talk regularly about whether you still need treatment with MINIVELLE.

MINIVELLE should not be used if you have unusual vaginal bleeding, currently have or have had certain cancers, had a stroke or heart attack, currently have or have had blood clots, currently have or have had liver problems, have been diagnosed with a bleeding disorder, are allergic to MINIVELLE or any of its ingredients, or think you may be pregnant.

Before you take MINIVELLE, tell your healthcare provider if you have unusual vaginal bleeding, have any other medical conditions, are going to have surgery or will be on bed rest, are breast feeding, and about all of the medicines you take.

The most common side effects that may occur with MINIVELLE are headache, breast tenderness, back and limb pain, common cold, upset stomach, nausea, inflammation of the sinuses and irregular vaginal bleeding or spotting.

MINIVELLE should be used at the lowest effective dose and for the shortest duration consistent with your treatment goals and risks.

These are not all the possible side effects of MINIVELLE. Please read the Patient Information section within the full Prescribing Information before taking MINIVELLE. For more information ask your healthcare provider or pharmacist for advice about side effects.

INDICATION

MINIVELLE® (estradiol transdermal system) is a prescription medicine patch that contains estradiol (an estrogen hormone). MINIVELLE is used to reduce moderate to severe hot flashes due to menopause and to help prevent postmenopausal osteoporosis (thin weak bones). The 0.025 mg/day dose is only approved for the prevention of postmenopausal osteoporosis.

If you use MINIVELLE only to prevent osteoporosis from menopause, talk with your healthcare provider about whether a different treatment or medicine without estrogens might be better for you.

Click here for the full Prescribing Information, including Boxed WARNING.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088.